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3 records

Peer reviewed2025Published

Ibogaine’s Potential Role in Supporting Reward System Recovery Across Diagnostic Boundaries (opens in a new tab)

Nicolas, M. Frontiers in Pharmacology, 16, Article 1744383.

A hypothesis and theory article examining whether ibogaine’s neurotrophic, dopaminergic, and glutamatergic actions may be relevant to shared reward system dysfunction across diagnostic categories. The proposed mechanism requires empirical validation.

Ibogaine · Reward system recovery · Transdiagnostic psychiatry

DOI 10.3389/fphar.2025.1744383

Preprint2026Public and evolving

Neural Attunement as a Post Acute Framework for Stabilizing Neuroplasticity (opens in a new tab)

Nicolas, M. Zenodo.

A developing framework for identifying a candidate post acute neural state and testing whether its regulatory dynamics change under standardized perturbation. Functional value is evaluated separately from state identification.

Post acute neuroplasticity · Electrophysiology · Regulation

DOI 10.5281/zenodo.20549391

Preprint2026Public manuscript

Cardiac Morphology During Drug-Induced QT Prolongation: An Educational Review Using Ibogaine as an Illustrative Exposure (opens in a new tab)

Nicolas, M. ResearchGate.

An educational review of ECG morphology during drug induced QT prolongation, using ibogaine as an illustrative exposure. The October 2026 revision addresses QT measurement, heart rate correction, serial change, and the limits of morphology interpretation.

Cardiac safety · ECG interpretation · Ibogaine

DOI 10.13140/RG.2.2.26351.09127/1